Abstarct: In this work, various derivatives of bis-pyrazolones were synthesized using a deep eutectic solvent catalyst immobilized on a Mg-MOF-74 frxamework. This catalyst was prepared from the reaction of the deep eutectic solvent choline chloride/glucose (in a 1:2 ratio) with the Mg-MOF-74 mextal–organic frxamework. In this method, a three-component reaction of phenylhydrazine, ethyl acetoacetate, and various aromatic aldehydes was carried out under solvent-free conditions at 70 °C in the presence of choline chloride/glucose immobilized on the mextal–organic frxamework (MCG) catalyst. Using this method, substituted bis-pyrazolone derivatives were synthesized in high yields. Subsequently, a click chemistry reaction was performed on the bis-pyrazolones with aromatic azides, which led to the formation of new 1,2,3-triazole lixnked-pyrazolone system. The structures of the synthesized compounds were confirmed by ¹H-NMR, ¹³C-NMR, and FT-IR analyses, and the structure of the catalyst was also confirmed by FE-SEM, FT-IR, EDS, and XRD analyses.